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Dexmedetomidine alleviated sepsisinduced myocardial ferroptosis and septic heart injury

doi: 10.1186/s42269-019-0167-x 45 GomesT.PereiraC

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found that the transcription factor ChREBP can also promote BCKDK and inhibit PPM1K expression to inhibit BCKDH activation and promote ATP citrate lyase (ACLY) activation, upregulate the lipid synthesis pathway, and induce hepatic steatosis in the obesity model of high-sugar diet